Desquinolinyl Lenvatinib CAS 796848-79-8 Purity >99.0% (HPLC) Lenvatinib Mesylate Intermediate Factory

Short Description:

1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea

Synonyms: Desquinolinyl Lenvatinib

CAS: 796848-79-8

Purity: >99.0% (HPLC)

Appearance: Off-White to Reddish Brown Solid Powder

Intermediate of Lenvatinib Mesylate CAS 857890-39-2

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Product Detail

Product Tags

Description:

Ruifu Chemical Supply Lenvatinib Mesylate Intermediates With High Purity
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib; 1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Chemical Properties:

Chemical Name	1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea
Synonyms	Desquinolinyl Lenvatinib; Lenvatinib Impurity 16; Lenvatinib Desquinolinyl Impurity; Lenvatinib Impurity LFS-A; Lenvatinib Mesylate Intermediate Ⅲ; N-(2-Chloro-4-Hydroxyphenyl)-N'-Cyclopropyl-Urea
CAS Number	796848-79-8
CAT Number	RF-PI1972
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C10H11ClN2O2
Molecular Weight	226.66
Boiling Point	364.6±42.0℃
Density	1.43±0.10 g/cm3
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	Off-White to Reddish Brown Solid Powder
Purity / Analysis Method	>99.0% (HPLC)
Moisture (K.F)	<0.50%
Residue on Ignition	<0.20%
Single Impurity	<0.50%
Total Impurities	<1.00%
Heavy Metals	<10ppm
Infrared Spectrum	Conforms to Structure
NMR	Conforms to Structure
Test Standard	Enterprise Standard
Usage	Intermediate of Lenvatinib Mesylate (CAS: 857890-39-2)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

FAQ:

Application:

1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea, also known as Desquinolinyl Lenvatinib, (CAS: 796848-79-8) is an intermediate or impurity of Lenvatinib Mesylate (CAS: 857890-39-2). Desquinolinyl Lenvatinib is a metabolite of Lenvatinib Mesylate which is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors. Lenvatinib is an anti-cancer drug for the treatment of certain kinds of thyroid cancer, and potentially for other cancers as well. On February 13, 2015, the US FDA approved anticancer drug Lenvatinib for the treatment of thyroid cancer. Lenvatinib is a multi-target enzyme inhibitor, being capable of inhibiting the VEGFR2 and VEGFR3 (vascular endothelial growth factor receptor). The trade name of Lenvatinib is Lenvima.